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启东是肝癌高发区,乙型肝炎的发病率也较高。自从1982年对启东地区新生儿进行乙肝疫苗预防接种工作以来,儿童的HHV感染率明显下降,但仍有少数由各种原因引起免疫失败而出现HBsAg阳性的儿童。为了解这些儿童丁型肝炎(HDV)的感染情况,采用酶标法对其进行血清HDAg和抗-HDV测定,并以同龄未接种乙肝疫苗的HBsAg阳性儿童作为对照。另对肝癌患者进行HDV调查,作为启东地区与国内其他地区丁型肝炎发病率的对照比较。
Qidong is a high incidence of liver cancer, hepatitis B incidence is higher. Since the hepatitis B vaccine vaccination was done for newborns in Qidong district in 1982, the incidence of HHV infection in children has dropped markedly. However, there are still a few children with HBsAg positive who have failed to achieve the immunization due to various reasons. Serum HDAg and anti-HDV were measured by enzyme-linked immunosorbent assay (ELISA) in order to understand the prevalence of hepatitis B virus (HDV) infection in these children. HBsAg-positive children who did not receive hepatitis B vaccine of the same age were used as controls. Another HDV survey of patients with liver cancer as a comparison of the incidence of hepatitis D in Qidong and other parts of the country.