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[目的]观察不同剂量大黄制剂保留灌肠治疗早期尿毒症的临床疗效。[方法]将符合入选标准的60例早期尿毒症患者随机分为低剂量组(30例)和高剂量组(30例),分别给予10g和25g生大黄制剂保留灌肠,12天为1个疗程。观察症状和体征以及血肌酐的变化情况。[结果]高剂量组疗效优于低剂量组(P<0.05)。[结论]25g生大黄制剂保留灌肠治疗早期尿毒症患者的临床疗效优于较低剂量组。
[Objective] To observe the clinical efficacy of different doses of rhubarb retention enema in the treatment of early uremia. [Methods] Sixty patients with early uremia who met the inclusion criteria were randomly divided into low dose group (30 cases) and high dose group (30 cases), and received rhubarb with 10g and 25g respectively. The enema was preserved for 12 days for one course . Observation of symptoms and signs and changes in serum creatinine. [Result] The efficacy of high-dose group was better than that of low-dose group (P <0.05). [Conclusion] The clinical efficacy of 25g rhubarb retention enema in patients with early uremia is better than that of lower dose group.