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目的观察益气养阴、活血祛浊治疗2型糖尿病的临床疗效观察。方法将200例新发2型糖尿病(病程小于3年、无明显并发症的病人),按入组顺序随机分为治疗组110例(其中有预实验的20例),对照组90例。2组病人在均接受二甲双胍、瑞格列奈降糖治疗,治疗组同时加服中药治疗。观察2组病人空腹血糖(FBG)、餐后2小时血糖(餐后2hBG)、空腹胰岛素(FINS)、糖化血红蛋白(GHbAIc)、胆固醇(CH)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、胰岛素指数(ISI)、症状体征等指标治疗前后变化。结果治疗组治疗前后比较,两组FBG、餐后2hBG、GHbAIc、CH、TG、LDL、ISI、症状体征,具有显著差异(P<0.05),与对照组比较,差异有显著意义(P<0.05)。结论运用中药益气养阴、活血祛浊法中药益气降浊汤能显著改善2型糖尿病症状体征,改善胰岛素抵抗,未发现不良反应。
Objective To observe the curative effect of type 2 diabetes mellitus on invigorating qi and nourishing yin and activating blood circulation and removing turbidity. Methods 200 cases of newly diagnosed type 2 diabetes mellitus (duration less than 3 years without obvious complication) were randomly divided into treatment group (110 cases), pretreatment group (20 cases) and control group (90 cases). Patients in both groups were treated with metformin and repaglinide, and the treatment group was given traditional Chinese medicine. The fasting blood glucose (FBG), postprandial blood glucose (2hBG), fasting insulin (FINS), GHbAIc, cholesterol, triglyceride, LDL), high density lipoprotein (HDL), insulin index (ISI), symptoms and signs and other indicators before and after treatment changes. Results Compared with the control group, there were significant differences in FBG, postprandial 2hBG, GHbAIc, CH, TG, LDL, ISI, symptom and signs between the two groups (P <0.05 ). Conclusion The traditional Chinese medicine Yiqi Yangyin, Huoxue Qumai method can significantly improve symptoms and signs of type 2 diabetes mellitus, improve insulin resistance and found no adverse reactions.