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目的:探讨短期大剂量静脉注射丙种球蛋白联合地塞米松治疗重症病毒性脑炎疗效。方法:对近来收治的70例重症病毒性脑炎随机分为两组,治疗组在对照组治疗的基础上应用静脉丙种球蛋白以0.4 mg/(kg.d)联合地塞米松0.5 mg/(kg.d)1 mg/(kg.d),连用3 d5 d。结果:在退热、呕吐缓解、神经精神症状、后遗症及死亡病例差异均有显著性。结论:早期用静脉丙种球蛋白联合地塞米松治疗重症病毒性脑炎可改善预后。
Objective: To investigate the short-term high-dose intravenous gamma globulin combined with dexamethasone in the treatment of severe viral encephalitis. Methods: Seventy patients with severe viral encephalitis were randomly divided into two groups. The treatment group was given intravenous gamma globulin (0.4 mg / (kg.d)) combined with dexamethasone 0.5 mg / ( kg.d) 1 mg / (kg.d) for 3 days d5 d. Results: There were significant differences in fever, vomiting, neuropsychiatric symptoms, sequelae and death cases. Conclusion: The early use of intravenous gamma globulin combined with dexamethasone in the treatment of severe viral encephalitis can improve the prognosis.