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作者选择95例ASAⅠ～Ⅱ级择期手术患儿,其中0.2～2岁30例,2.1～5岁38例,学龄儿童27例.按不同年龄随机分为四组,组Ⅰ(n=24)、组Ⅱ(n=23)于麻醉诱导前鼻腔滴入咪唑安定0.2mg/kg;组Ⅲ(n=24)、组Ⅳ(n=24)鼻腔滴入舒芬太尼2μg/kg;组Ⅲ(n=24)10min后组Ⅰ、Ⅲ吸0.5～4%氟烷,插气管导管;组Ⅱ、Ⅳ静注硫贲妥钠3mg/kg、泮库溴铵0.1mg/kg再吸氟烷诱导插管.四组均用70%N_2O-O_2-氟烷维持麻醉,控制潮气末CO_2分压在35～40mmHg.用改良Wilton氏镇静程度评分法判定患儿行为反应;4级法判定胸壁顺应性并连续测定SpO_2和心率.最后于抱离父母以及诱导前综合上述三项判定效果与安全性为三级:(1)良好:无焦虑,SpO_2>95%,控制通气容易.(2)满意:轻度哭闹,SpO_290～95%,轻度胸壁紧张.(3)欠佳:抱离父母有困难,哭闹,需改麻醉.用药前各组间哭闹率无明显差异.咪唑安定组在
Ninety-five children undergoing ASA Ⅰ ~ Ⅱ elective surgery were enrolled in this study, including 30 children aged 0.2-2 years, 38 children aged 2.1-5 years and 27 children of school age.All patients were randomly divided into four groups according to different ages: group Ⅰ (n = 24) Group Ⅱ (n = 23) was given nasal diazepam 0.2mg / kg before the induction of anesthesia; sufentanil 2μg / kg was given to the rats in group Ⅲ (n = 24) n = 24) After 10 min, rats were anesthetized with 0.5 to 4% halothane by intubation, and then intubated with a tracheal catheter. Groups Ⅱ and Ⅳ were given sodium thiophanate 3 mg / kg and pancuronium 0.1 mg / kg respectively. Tube.The anesthesia was maintained in all the four groups with 70% N 2 O 2 -fluorane, and the partial pressure of CO 2 was controlled at 35 ~ 40mmHg.Wild Wilton’s sedation score was used to determine the behavioral response in children, SpO2 and heart rate were measured continuously.Finally, the above-mentioned three judgments of effect and safety were three levels: (1) good: no anxiety, SpO_2> 95%, easy to control ventilation. (2) Satisfaction: Degree of crying, SpO_290 ~ 95%, mild chest wall tension. (3) Poor: hold away from their parents have difficulties, crying, need to change anesthesia .Before treatment, crying rate between groups no significant difference.