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目的探讨血培养联合超敏C反应蛋白与降钙素原检查在新生儿败血症中的临床应用。方法采用电化学发光法和免疫散射比浊法分别测定新生儿败血症患儿的降钙素原、超敏C反应蛋白浓度,并与血培养结果比较。结果与对照组相比,败血症组患儿的降钙素原和超敏C反应蛋白明显升高,差异有统计学意义。结论超敏C反映蛋白与降钙素原可作为新生儿败血症快速有效诊断参考指标和评估病情的检测指标。
Objective To investigate the clinical application of blood culture combined with high-sensitivity C-reactive protein and procalcitonin in neonatal sepsis. Methods The concentrations of procalcitonin and high-sensitivity C-reactive protein in children with neonatal sepsis were determined by electrochemiluminescence and immune nephelometry, respectively, and compared with the results of blood culture. Results Compared with the control group, procalcitonin and hypersensitive C-reactive protein in sepsis group were significantly increased, the difference was statistically significant. Conclusion The hypersensitive C-reactive protein and procalcitonin can be used as a quick and effective reference for the diagnosis of neonatal sepsis and as a detection indicator of the disease.