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目的：探讨溴隐亭对女性高催乳素血症的疗效。方法：高催乳素血症 ８６例（２９ ａ± ｓ ６ ａ），用溴隐亭 １．２５ ｍｇ，ｐｏ， ｂｉｄ， ４ ｄ后无副作用增至２．５ｍｇ，ｐｏ，ｂｉｄ～ｑｉｄ（根据情况调整剂量）。结果：７３例服药 ５ ｍｐ·ｄ~(-1)者，1 ｍｏ时催乳素（ＰＲＬ）下降（５４± １５）％， １３例服药 ７． ５～１０ ｍｇ·ｄ~(-1)者 ＰＲＬ下降（６８± １６）％。服药 ６ ｍｏ， １２例垂体大腺瘤直径缩小 ０． ７０ ｃｍ± ０． １２ ｃｍ（０． ６～０． ９ ｃｍ）， ２例治疗 １ａ后腺瘤消失。停止滥乳时用药量为 ３１２ ｍｇ± ２７ｍｇ，恢复排卵时用药量为 ４５２ ｍｇ± ４３ ｍｇ。结论；溴隐亭治疗高催乳素血症疗效显著，且能使垂体催乳素瘤缩小甚至消失。
Objective: To investigate the effect of bromocriptine on female hyperprolactinemia. Methods: Eighty-six patients with hyperprolactinemia (29 a ± s 6 a) were treated with bromocriptine 1.25 mg, po, bid for 4 days without side effects to 2.5 mg, po, bid ~ qid Adjust the dose). Results: In 73 patients who took 5 mp · d -1, the PRL decreased by 54 ± 15% at 1 month and 13 cases took medicine. The PRL decreased by (68 ± 16)% at 5 to 10 mg · d -1. Taking 6 months, 12 cases of pituitary adenoma reduced diameter 0. 70 cm ± 0. 12 cm (0. 6 ~ 0. 9 cm), two cases of adenoma disappeared after treatment of 1a. To stop the abuse of milk dose of 312 mg ± 27mg, ovulation recovery dose of 452 mg ± 43 mg. Conclusion; Bromocriptine treatment of hyperprolactinemia significant effect, and can make pituitary prolactinoma shrink or even disappear.