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患儿,男,4岁,进行性面色苍白2个半月入院。重度贫血貌,皮肤无出血点,浅表淋巴结无肿大,肝剑下2cm,脾未及。血WBC4.8×10~9/L,中性10％,淋巴90％,Hb53g/L,PC80×10~9/L。拟再生障碍性贫血收入院。骨髓象:增生极度活跃,多毛细胞占96％,过氧化酶染色(-),酸性磷酸酶(+),胞体直径15～20微米,大小不等,核园形或卵园形,染色质呈粗网状,核仁不明显,胞浆量少,呈浅灰色,胞浆边缘呈毛发状和伪足样突出。粒、红及巨核三系均受抑制。采用HOAP方案治疗1个疗程后病情无明显改善,化验检查:WBC4.2×10
Children, male, 4 years old, progressive pale 2 and a half months admitted. Severe anemia appearance, skin no bleeding, superficial lymph nodes without swelling, liver sword 2cm, spleen is not. Blood WBC 4.8 × 10 ~ 9 / L, neutral 10%, lymph 90%, Hb53g / L, PC80 × 10 ~ 9 / L. Pseudo aplastic anemia income homes. Bone marrow: hyperplasia extremely active, hair cells accounted for 96%, peroxidase staining (-), acid phosphatase (+), cell body diameter of 15 to 20 microns in size, nuclear or oval park-shaped, chromatin was Coarse reticular, nucleolus is not obvious, less cytoplasm, light gray, cytoplasmic hairy and pseudopodia prominent. Granules, red and megakaryocytes were suppressed. HOAP program after treatment with a course of illness no significant improvement in laboratory tests: WBC4.2 × 10