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目的 观察通痹汤与氨甲喋呤联合治疗类风湿关节炎疗效。方法 治疗组采用中药通痹汤与氨甲喋呤联合治疗类风湿性关节炎（ＲＡ）７９例，以风湿液与氨甲喋呤联合治疗的４０例ＲＡ作对照。其中治疗组１８例，对照组９例。结果与结论 两组疗效均比文献所报告的单用氨甲喋呤疗效为佳。而通痹汤更具较强的抗炎镇痛及免疫调节作用，可使关节肿痛症状迅速消失，关节功能明显改善，晨僵时间消失或缩短，并随着关节炎症的减轻，使血液中ＩｇＧ，ＩｇＭ，ＩｇＡ恢复正常，血沉下降曲线平稳，类风湿因子（ＲＦ）阴转率达６７．５７％。用药后撤停激素快，无反跳现象，副作用少。骨质修复作用明显，具有改善病情作用。其疗效明显优于对照组。
Objective To observe the therapeutic effect of Tongbi Decoction combined with methotrexate on rheumatoid arthritis. Methods The treatment group was treated with Tongbi Decoction and methotrexate in combination with rheumatoid arthritis (RA) in 79 cases. Rheumatoid arthritis and methotrexate combined treatment of 40 cases of RA as a control. 18 cases in the treatment group and 9 cases in the control group. Results and Conclusion The efficacy of methotrexate alone was better than that reported in the literature. And tongbi decoction more strong anti-inflammatory and analgesic and immunomodulatory effects, can quickly disappear symptoms of joint swelling and pain, joint function improved significantly, morning stiffness disappeared or shortened, and with the reduction of joint inflammation, the blood IgG, IgM, IgA returned to normal, the decline of erythrocyte sedimentation rate curve stable, rheumatoid factor (RF) negative conversion rate of 67.57%. Withdrawal withdrawal hormone fast, no rebound phenomenon, fewer side effects. Bone repair obvious role, with the effect of improving the condition. The efficacy was significantly better than the control group.