用基因工程技术生产抗体,并赋予其许多新的特性,极大地拓展了抗体的功能及其在临床上的应用范围.PCR技术为获得抗体基因提供了有效、快捷的实验手段,噬菌体表面表达技术简化了高异质性抗体基因的获得,DNA重组技术使体外生产抗体成为可能.低成本、人源化及双特异等诸多特点使基因工程抗体在治疗和诊断上的应用更加广泛.根据最近文献对基因工程抗体及其应用前景进行了综述.“,”The antibodies can now be produced by engineering technology and its functions or clinical applications widely developed. A valid and rapid method of obstaining antibody gene is provided by PCR, the procession of acquring heterogenous antibody moleculars is simplified by phage display technology, antibodies can be produced in vitro by DNA recombinant technology. The genetic engineering antibodies have been widely used in clinical dignosis and treatment for the advantages of low cost, humanization and bi...