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目的探讨米非司酮联合甲氨蝶呤在治疗不同血β-人绒毛膜促性腺激素(β-HCT)值的宫外孕的疗效。方法选取321例宫外孕住院患者,所有患者给予米非司酮联合甲氨蝶呤治疗。根据血β-HCG浓度不同分组,β-HCG≤1000U/L为A组,1000U/L<β-HCG≤2000U/L为B组。β-HCG>2000U/L为C组,统计各组患者的治愈率,比较各组的差异。结果 321例患者,成功246例,总治愈率为76.6%。其中,A组56例,成功47例,治愈率为83.9%;B组176例,成功139例,治愈率为79.0%,C组89例,成功60例,治愈率为67.4%;A组与C组、B组与C组治愈率比较,差异有统计学意义。A组与B组治疗率比较,差异无统计学意义(P>0.05)。结论米非司酮联合甲氨蝶呤治疗宫外孕疗效显著,在β-HCG≤2000 U/L时,效果更加明显。
Objective To investigate the efficacy of mifepristone combined with methotrexate in the treatment of ectopic pregnancy with β-HCT in different blood. Methods 321 cases of ectopic pregnancy inpatients, all patients given mifepristone combined methotrexate treatment. According to different blood β-HCG concentration group, β-HCG≤1000U / L for the A group, 1000U / L <β-HCG≤2000U / L for the B group. β-HCG> 2000U / L for the C group, the cure rate of each group statistics, the differences between the groups were compared. Results 321 patients, 246 cases of success, the total cure rate was 76.6%. In group A, 56 cases were successful and 47 cases were successful. The cure rate was 83.9%. In group B, 176 cases were successfully treated with 139 cases. The cure rate was 79.0%. In group C, 89 cases were successful and 60 cases were cured. The cure rate was 67.4% C group, B group and C group cure rate, the difference was statistically significant. There was no significant difference in the treatment rates between group A and group B (P> 0.05). Conclusion Mifepristone combined with methotrexate treatment of ectopic pregnancy significant effect, in the β-HCG ≤ 2000 U / L, the effect is more pronounced.