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观察了自制的平阳霉素磁性明胶微球对人舌癌Ｔｃａ８１１３细胞株的体外杀伤作用及对人舌癌裸鼠移植瘤的治疗效果。结果表明，平阳霉素磁性明胶微球和游离平阳霉素均具有杀伤肿瘤细胞的作用，二者之间无显著性差异（Ｐ＞００５），体内实验中，平阳霉素磁性明胶微球对人舌癌移植瘤有明显的抑制作用，抑瘤率为８５３３％，明显高于游离平阳霉素（３５９％），而对正常组织的毒副作用明显减轻。
The killing effect of homemade Pingyangmycin magnetic gelatin microspheres on human tongue cancer Tca8113 cell line in vitro and the therapeutic effect on human tongue cancer xenografts in nude mice were observed. The results showed that both the Pingyangmycin magnetic gelatin microspheres and the free Pingyangmycin had the effect of killing the tumor cells, and there was no significant difference between the two (P>0.05). In the in vivo experiment, Pingyangmycin magnetic gelatin microspheres The inhibitory effect on human tongue cancer xenografts was obvious. The tumor inhibition rate was 8533%, which was significantly higher than that of free pingyangmycin (359%). The side effects on normal tissues were significantly reduced.