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缬草挥发油及提油后的药渣以不同浓度(60~85%)乙醇渗漉制取的浸膏粉都具有镇痛作用,浸膏的镇痛作用随乙醇浓度升高而增强,浸膏的镇痛作用高于挥发油。缬草挥发油有突出的平滑肌解痉作用,85%乙醇制取的浸膏有缓和的解痉作用,60%乙醇制取的浸膏则无解痉作用。缬草挥发油与浸膏在解痉、镇痛上有良好的协同作用。缬草药材随干燥与贮放含油率严重下降,挥发油稳定性差。缬草制剂制备时宜用新鲜药材蒸馏-85%乙醇渗漉二步提取,挥发油以β-环糊精包结
The extracts of the volatile oil from the barnyardgrass and the dregs from the oil extract with different concentrations (60 to 85%) of ethanol can all have analgesic effect. The analgesic effect of the extract increases with the increase of ethanol concentration. The analgesic effect is higher than the volatile oil. Herba volatile oil has outstanding smooth muscle spasm, 85% ethanol extracts have a mild antispasmodic effect, and 60% ethanol extracts have no antispasmodic effect. Herba volatile oil and extract have a good synergistic effect on spasmolysis and analgesia.缬 缬 缬 缬 缬 缬 缬 缬 缬 缬 缬 缬 缬 缬 缬 缬 缬 缬 缬. Herba preparations should be prepared with fresh herbs distilling -85% ethanol percolation two-step extraction, volatile oil with β-cyclodextrin inclusion