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目的:探讨维吾尔族脑血管病的危险因素。方法:住院的维吾尔族脑血管病患者进行了1:1配对的病例对照研究,研究病例符合1995年全国脑血管病学术会议修订的诊断标准,对照病例为同期入院、同民族、同性别,相似年龄组,且无脑血管病史的非脑血管病患者。采用同一调查表,对83对病例及其对照进行了调查,收集有关爱好、习惯、家族史、既往史等27个因素的暴露情况。应用logistic回归模型对27个暴露变量进行了单因素筛选及多因素分析。结果:单因素分析筛选出8个有意义的变量,其中7个为危险因素,分别是少食水果、蔬菜、喜咸食、经常夜间工作、家族史、高血压病史、关节病史、肥胖。多因素logistic回归分析,OR分别为:10.68(家族史)、10.00(经常夜间工作)、6.66(高血压病史)、6.28(喜咸食)。结论:家族史、经常夜间工作、高血压病史、喜咸食可能是维吾尔族脑血管病的主要危险因素。
Objective: To investigate the risk factors of cerebrovascular disease in Uighur. Methods: A case-control study on in-hospital Uygur patients with cerebrovascular disease was conducted. The study matched the diagnostic criteria revised by the National Conference on Cerebrovascular Disease in 1995. The control cases were hospitalized in the same period, same ethnic group, same-sex, similar Age group, and no history of cerebrovascular disease in patients with non-cerebrovascular disease. Using the same questionnaire, 83 pairs of cases and their controls were investigated and 27 exposure profiles of hobbies, habits, family history and past history were collected. Logistic regression model was used to univariate and multivariate analysis of 27 exposure variables. Results: Eight significant variables were screened by univariate analysis. Seven of them were risk factors. They were eating less fruits, vegetables, salty foods, frequent night work, family history, history of hypertension, history of joint disease and obesity. Multivariate logistic regression analysis showed ORs of 10.68 (family history), 10.00 (frequent nighttime work), 6.66 (history of hypertension) and 6.28 (salty eaters). Conclusion: Family history, frequent night work, history of hypertension, and salty eaters may be the main risk factors of cerebrovascular disease in Uighur.