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本研究采用免疫组化（ＡＢＣ）法，对６６例食管癌组织及２１例正常人食管组织进行雌激素受体（ＥＲ）和孕激素受体（ＰＲ）的检测。结果发现：正常人食管组织不含ＥＲ、ＰＲ；食管癌组织ＥＲ阳性率为４２．４２％（２８／６６），ＰＲ阳性率为４３．９４％（２９／６６）。受体水平与食管癌患者性别、癌分化程度相关，而与年龄、ＴＮＭ分期及有无淋巴结转移无关。结果表明：采用ＡＢＣ法检测石蜡包埋的食管癌组织ＥＲ和ＰＲ具有可靠性和敏感性；检测食管癌ＥＲ、ＰＲ，可为估价预后和指导临床进行内分泌治疗提供参考。
In this study, the estrogen receptor (ER) and progesterone receptor (PR) were detected in 66 esophageal cancer tissues and 21 normal esophageal tissues by immunohistochemistry (ABC). The results showed that: normal esophageal tissue does not contain ER, PR; esophageal cancer tissue ER positive rate was 42.42% (28/66), PR positive rate was 43.94% (29/66). Receptor levels were associated with gender and cancer differentiation in patients with esophageal cancer, but not with age, TNM stage, and lymph node metastasis. The results showed that the reliability and sensitivity of ER and PR in paraffin-embedded esophageal cancer tissues were detected by ABC method. Detection of ER and PR in esophageal cancer could provide reference for the evaluation of prognosis and guidance of clinical endocrine therapy.