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氮芥类(Nitrogen Mustard)药物治疗腫瘤,目前被認为系抑制腫瘤细胞生長的有效药物,基中鉴酸三氯三乙基胺(簡称HN_3),鹽酸甲基双(β—氯乙基)胺(簡称HN_2),一向用于临床。美国医学杂誌1946年132卷中有Goodman等之一篇报告,詳細叙述了此二药物的疗效。不久后,鹽酸甲基双(β—氯乙基)胺—N一氧化物(简称Nitromin,今暫定中文名癌得平)問世,因其毒性低,疗效好,使用亦较安全。氮芥类的治疗,据称有与放射治疗相同的效果,有些病人用放射治疗不能获得进展,用氮芥类治疗,较有
Nitrogen Mustard drug treatment of cancer, is currently considered to be effective drugs to inhibit tumor cell growth, the base of trichlorethyl trichloride (referred to as HN_3), methyl bis (β-chloroethyl ) Amine (referred to as HN_2), has always been used in clinical. A report by Goodman et al. In the American Medical Journal, Volume 13, 1946, details the efficacy of the two drugs. Shortly after, methyl bis (β-chloroethyl) amine-N monoxide hydrochloride (referred to as Nitromin, now tentatively Chinese name cancer level) came out, because of its low toxicity, good efficacy, the use of safer. The treatment of nitrogen mustards is said to have the same effect as radiotherapy, and some patients can not make progress with radiation and are treated with nitrogen mustards,