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为了评价生长激素缺乏症(GHD)患者左心室功能,用平衡法核素心室造影测定了35例童期生长激素缺乏症患者左心室收缩与舒张功能。结果表明,40％GHD患者左心室收缩功能低下,其中81％为左心室局部收缩功能受损。在舒张功能低下的16例患者中,有11例收缩功能异常。结果提示舒张功能异常早于整体收缩功能异常,而心室局部收缩功能异常则较舒张功能和整体收缩功能异常更早出现。因此,对儿童GHD患者应尽早检测心功能,以预防成年后心血管疾病的发生。
To assess left ventricular function in patients with growth hormone deficiency (GHD), the left ventricular systolic and diastolic function in 35 patients with growth hormone deficiency in childhood was measured by equilibrium-phase radionuclide venography. The results showed that 40% of GHD patients with left ventricular systolic dysfunction, of which 81% of left ventricular regional systolic dysfunction. Among 16 patients with diastolic dysfunction, 11 had contractile dysfunction. The results suggest that diastolic dysfunction is earlier than the overall systolic dysfunction, whereas ventricular local systolic dysfunction occurs earlier than diastolic and global systolic dysfunction. Therefore, the detection of cardiac function in children with GHD as soon as possible to prevent the occurrence of cardiovascular disease in adulthood.