论文部分内容阅读
目的总结特发性低颅压头痛临床特点及预后因素。方法对2010年12月1日-2014年2月1日的特发性低颅压综合征住院患者进行连续登记。在患者首次就诊时,研究者收集其基本信息及临床特点,安排常规检查及腰椎穿刺脑脊液检查。患者均接受固定体位及补液治疗。治疗1周后随访。在治疗前和随访时应用视觉模拟评分法(VAS)评估患者头痛的严重程度。结果共纳入110例特发性低颅压头痛患者,其中男39例(35.5%),女71例(64.5%);发病年龄17~91岁,平均(42.0±12.4)岁。除体位相关的头痛外,较为常见的临床表现为恶心68例(61.8%),呕吐63例(57.3%),头昏40例(36.4%),颈部疼痛27例(24.5%),耳鸣23例(20.9%)。入组时VAS评分为(7.46±0.86)分,1周后随访VAS评分为(3.45±2.17)分,平均改善百分比为53.75%。入院筛查抗核抗体阳性患者预后改善更好。结论特发性低颅压头痛可伴有多种脑干或小脑症状、脑膜刺激症状,脑脊液可呈现类似病毒感染的表现,但通常血清病毒筛查阴性,如不能通过影像学寻找到脑脊液漏破口,则可予以适当补液,并辅助以体位治疗,大多数患者能够得到明显改善。
Objective To summarize the clinical features and prognostic factors of idiopathic low intracranial pressure headache. Methods The hospitalized patients with idiopathic low intracranial pressure syndrome were enrolled continuously from December 1, 2010 to February 1, 2014. At the first visit of the patient, the researchers collected their basic information and clinical features, arranged routine examination and lumbar puncture cerebrospinal fluid examination. Patients received fixed body and fluid treatment. Follow up after 1 week of treatment. Visual analogue scale (VAS) was used to assess the severity of headache in patients before and at follow-up. Results A total of 110 patients with idiopathic low intracranial pressure headache were enrolled, including 39 males (35.5%) and 71 females (64.5%). The age of onset was from 17 to 91 years (mean, 42.0 ± 12.4 years). In addition to body-related headache, the more common clinical manifestations were nausea in 68 (61.8%), vomiting in 63 (57.3%), dizziness in 40 (36.4%), neck pain in 27 (24.5%), tinnitus Example (20.9%). The VAS score was (7.46 ± 0.86) points at follow-up and VAS score was (3.45 ± 2.17) at follow-up one week later, with an average improvement rate of 53.75%. Admission screening anti-nuclear antibody positive prognosis better. Conclusions Idiopathic low intracranial pressure headache may be accompanied by a variety of brain stem or cerebellar symptoms and meningeal irritation. Cerebrospinal fluid may show virus-like symptoms. However, serum virus screening is usually negative. If cerebrovascular leakage can not be found through imaging Mouth, you can be an appropriate rehydration, and assisted with the position of treatment, most patients can be significantly improved.