1965年Lippes作出了塑料宫内节育器安全有效的结论后,在全世界开始推广。其副作用有脱环、出血、疼痛、偶有子宫穿孔,但不严重。急性盆器炎很少,应用抗菌素门诊治疗即可。1966年Tietre报道使用宫内节育器(简称IUD)合并急性盆器炎100例,但否认其有因果关系。1968年Scott等报道使用IUD合并急性盆器炎369例,有10例死亡。同年Wright报道82例使用IUD发病率为6.6％,约 Lippes made a safe and effective conclusion of the plastic IUD in 1965 and started the promotion worldwide. Side effects of its ring, bleeding, pain, occasional uterine perforation, but not serious. Acute pelvic inflammatory disease rarely, the application of antibiotic clinic treatment can be. Tietre reported in 1966 the use of intrauterine devices (IUD) combined with acute pelvic inflammatory disease in 100 cases, but denied a causal relationship. Scott and other reports in 1968, the use of IUD combined acute pelvic inflammatory disease 369 cases, 10 patients died. The same year Wright reported 82 cases of IUD incidence of 6.6%, about