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目的探讨胆囊癌的临床特点和诊治方法的选择。方法对1995~2006年间收治的36例胆囊癌患者的临床资料进行回顾性分忻。结果24例(66.7%)有胆囊癌合并胆囊结石;中晚期病例有31例(86.1%),合并肝功能异常者17例(47.2%)。手术切除率为66.7%,其中行根治性切除10例,根治率为29.4%。根治性手术的1、3年生存率分别为40%、10%;姑息性手术的1、3年生存率分别为16.7%、0。结论胆囊癌的发病率上升且与胆囊结石关系密切,早期诊断与治疗是提高生存率的关键。
Objective To investigate the clinical features and diagnosis and treatment of gallbladder cancer. Methods The clinical data of 36 patients with gallbladder carcinoma admitted from 1995 to 2006 were retrospectively analyzed. Results Twenty-four patients (66.7%) had cholecystolithiasis with cholecystolithiasis. There were 31 cases (86.1%) in the advanced stage and 17 cases (47.2%) with the hepatic dysfunction. Surgical resection rate was 66.7%, of which 10 were radical resection, the cure rate was 29.4%. The 1-year and 3-year survival rates of radical surgery were 40% and 10%, respectively. The 1-year and 3-year survival rates of palliative surgery were 16.7% and 0%, respectively. Conclusions The incidence of gallbladder cancer is rising and closely related to gallstone. Early diagnosis and treatment are the keys to improve the survival rate.