论文部分内容阅读
目的探讨不同消毒液对胃肠道吻合口愈合的影响及影响程度,试图筛选出适合胃肠道吻合口的最佳消毒方法。方法对50只家兔实行胃-空肠、空肠-空肠单层缝合,随机分成5组,分别用不同消毒液消毒拟吻合组织黏膜;并在术后3、7 d取家兔腹水大肠埃希菌测定,在术后3、71、0 d留取吻合口标本检测吻合口破裂压、吻合口组织中胶原纤维含量测定。结果 5组死亡数差异无统计学意义;生理盐水组、乙醇组、聚维酮碘组、碘酊组和氯己定组腹水大肠埃希菌测定:术后3 d检测阳性率分别为50.0%、33.3%、11.1%、30.0%和22.2%,差异无统计学意义,术后7 d检测阳性率分别为80.0%、55.6%、22.2%、60.0%、88.9%,差异有统计学意义(P<0.01,χ2=34.55)。结论不同消毒液对胃肠道吻合口愈合的影响不同,聚维酮碘是胃肠道吻合口消毒最为理想的消毒液。
Objective To investigate the effect of different disinfectants on the healing of gastrointestinal anastomosis and the influence of different disinfectants on the healing of gastrointestinal anastomosis in order to select the best disinfection method suitable for gastrointestinal anastomosis. Methods Fifty rabbits were stained with stomach-jejunum, jejunum and jejunum. The rabbits were randomly divided into five groups. The mucosa of the rabbits were disinfected with different disinfectants, and the ascites Escherichia coli Determination of anastomotic specimens at 3,71,0 d after operation to detect anastomotic rupture pressure, collagen content in the anastomosis tissue. Results There was no significant difference in the number of deaths among the 5 groups. In the saline group, alcohol group, povidone-iodine group, iodine tincture group and chlorhexidine group, the positive rates of ascites were 50.0% 33.3%, 11.1%, 30.0% and 22.2% respectively. There was no significant difference between the two groups (P> 0.05), and the positive rates at the seventh postoperative day were 80.0%, 55.6%, 22.2%, 60.0% and 88.9%, respectively 0.01, χ2 = 34.55). Conclusion Different disinfectants have different effects on gastrointestinal anastomosis healing. Povidone iodine is the best disinfectant for gastrointestinal anastomosis disinfection.