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目的探讨1992—2009年广东省高校新生HBsAg阳性率状况,为有效控制乙型肝炎流行提供依据。方法通过检索收集有关广东省高校新生HBsAg体检结果分析报道的文献,对广东省高校新生HBsAg检测人数、阳性人数进行统计分析。结果共计入选28篇文献,1992—2009年广东省高校新生HBsAg平均阳性率为13.45%(35 977/267 485),1992—2004年广东省高校新生HBsAg阳性率分别为20.49%,16.70%,16.73%,16.80%,16.52%,16.26%,15.06%,15.80%,17.37%,16.55%,15.25%,15.84%,16.26%,变化趋势不明显;2005—2009年分别为14.20%,11.52%,9.35%,8.78%,7.33%,呈逐年下降趋势,差异有统计学意义(P<0.05)。结论 1992—2004年广东省高校新生HBsAg阳性率维持在较高水平且变化趋势不明显,2005—2009年呈逐年下降趋势。
Objective To investigate the HBsAg positive rate of freshmen in colleges and universities of Guangdong Province from 1992 to 2009, and provide a basis for the effective control of hepatitis B epidemic. Methods By collecting and collecting the reports about the HBsAg results of freshmen in Guangdong Province, we analyzed the number of HBsAg positive persons and the number of freshmen in Guangdong colleges and universities. Results A total of 28 articles were selected. The average HBsAg positive rate was 13.45% (35 977/267 485) among freshmen in Guangdong province during 1992-2009. The positive rates of HBsAg in freshmen in Guangdong province from 1992 to 2004 were 20.49%, 16.70% and 16.73 The trend is not obvious; from 2005 to 2009, it is respectively 14.20%, 11.52%, 9.35%, 16.26%, 15.06%, 15.80%, 17.37%, 16.55%, 15.25%, 15.84% and 16.26% %, 8.78% and 7.33% respectively, showing a trend of declining year by year with a significant difference (P <0.05). Conclusions The positive rate of HBsAg among college freshmen in Guangdong Province during 1992-2004 was maintained at a high level with no significant change trend, showing a declining trend from 2005 to 2009.