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目的探讨糖尿病合并冠心病患者的临床与冠状动脉造影特点。方法回顾分析经冠状动脉造影确诊的冠心病患者227例,其中合并糖尿病患者(DM组)67例,不合并糖尿病患者(非DM组)160例,比较两组患者的空腹血糖、血脂、血压,观察其冠状动脉受累情况。结果DM组的甘油三酯(TG)、血浆致动脉粥样硬化指数(AIP)和空腹血浆葡萄糖浓度(FBG)明显高于非DM组(P<0.01)。吸烟数、收缩压及舒张压DM组均比非DM组高,但差异无统计学意义。DM组冠状动脉三支病变发生率(53.7%)明显高于非DM组(36.9%),而单支病变发生率(20.9%)显著低于非DM组(41.3%)(P<0.05),弥漫性病变发生率(64.2%)显著高于非DM组(45.0%)(P<0.05)。结论糖尿病合并冠心病患者中血脂异常高发,冠状动脉病变范围广泛,综合干预血糖及心血管病的其他高危因素,对防止冠心病的发生、发展及改善预后意义重大。
Objective To investigate the clinical characteristics and coronary angiography in patients with diabetes mellitus complicated with coronary heart disease. Methods A total of 227 coronary artery disease patients diagnosed by coronary angiography were retrospectively analyzed. Among them, 67 patients with diabetes mellitus (DM group) and 160 patients without diabetes mellitus (DM group) were compared. The fasting blood glucose, blood lipid, blood pressure, Observation of coronary artery involvement. Results The levels of triglyceride (TG), plasma atherogenic index (AIP) and fasting plasma glucose (FBG) in DM group were significantly higher than those in non-DM group (P <0.01). Smoking, systolic blood pressure and diastolic blood pressure DM group were higher than non-DM group, but the difference was not statistically significant. The incidence of coronary artery disease in DM group was significantly higher than that in non-DM group (53.7% vs 36.9%), while the incidence of single vessel disease was significantly lower in non-DM group (20.9% vs 41.3%, P <0.05) The incidence of diffuse lesions (64.2%) was significantly higher than that of non-DM patients (45.0%) (P <0.05). Conclusions In patients with diabetes mellitus and coronary heart disease, there is a high incidence of dyslipidemia and a wide range of coronary artery disease. Comprehensive intervention of other risk factors of blood glucose and cardiovascular diseases is of great significance in preventing the occurrence and development of coronary heart disease and improving prognosis.