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目的:评价头孢唑林钠对剖宫产患者围术期中预防用药的疗效与成本。方法:选取2015年1月—2015年7月间妇产科收治的需剖宫产产妇136例为观察对象,将其分为对照组和观察组,每组68例;对照组患者均给予头孢替安围术期治疗用药,观察组患者均给予头孢唑林钠围术期治疗用药,比较和评价两组患者围术期用药后的临床各指标。结果:两组患者围术期用药后的住院时间经比较其差异无统计学意义(P>0.05);观察组患者围术期用药后人均抗菌药物费用明显低于对照组(P<0.05),中性粒细胞计数、白细胞总数和体温恢复正常时间,以及子宫腔感染、切口感染和术后发生产褥病率等观察指标均明显优于对照组(P<0.05)。结论:剖宫产患者围术期给予头孢唑林钠治疗,有助于其产后的快速康复,缩短药物治疗时间,促进其生命体征指标的改善,其临床应用价值优于头孢替安。
Objective: To evaluate the efficacy and cost of cefazolin sodium in prophylactic use of cesarean section during perioperative period. Methods: 136 cases of cesarean section women who were admitted to obstetrics and gynecology department from January 2015 to July 2015 were selected as the observation objects and divided into control group and observation group, 68 cases in each group. The patients in control group were given cefazolin In the perioperative period, the patients in the observation group were given cefazolin sodium for perioperative treatment, and the clinical parameters in both groups were compared and evaluated. Results: Perioperative period after hospitalization in both groups showed no significant difference (P> 0.05). The per capita cost of antimicrobial drugs in perioperative period was significantly lower in the observation group than that in the control group (P <0.05) Neutrophil count, the total number of white blood cells and body temperature to restore normal time, as well as uterine cavity infection, incision infection and puerperal morbidity were observed indicators were significantly better than the control group (P <0.05). CONCLUSION: Cefazolin sodium is given during cesarean delivery in perioperative period, which is helpful to its rapid recovery after delivery, shortening the time of drug treatment and improving the vital signs of cesarean section. Its clinical value is better than that of cefotiam.