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目的探讨乙型肝炎后肝硬化并发糖代谢异常的临床特点。方法选取本院2009年1月~2012年12月96例乙型肝炎后肝硬化患者,经糖耐量检测,将其分成糖耐量异常组、糖调节健康组、糖尿病组,并选取32例健康者做对比,对其予以C肽释放检测,分析对比血糖(GLU)、胰岛素(INS)及C肽含量。结果糖耐量异常组、糖调节健康组和糖尿病组在胰岛素分泌指数、胰岛素抵抗指数方面无差异性,数值上升。结论乙型肝炎后肝硬化患者具有高胰岛素血症,其胰岛素敏感性下降,出现糖代谢异常需及时防治,首先确保血糖值正常。
Objective To investigate the clinical features of hepatitis B cirrhosis complicated with abnormal glucose metabolism. Methods Ninety-six patients with post-hepatitis B cirrhosis from January 2009 to December 2012 in our hospital were divided into two groups according to their glucose tolerance test: normal glucose tolerance group, healthy control group and diabetes mellitus group. 32 healthy subjects In contrast, C-peptide release was detected and the levels of GLU, INS and C-peptide were compared. Results There were no differences in insulin secretion index and insulin resistance index among the groups with impaired glucose tolerance, glucose-regulated healthy group and diabetes mellitus group. Conclusions Patients with posthepatitic cirrhosis have hyperinsulinemia and their insulin sensitivity is decreased. If abnormal glucose metabolism occurs, they should be prevented and controlled in time. First, the blood glucose level should be normal.