论文部分内容阅读
目的探讨临床外科手术治疗老年喉癌效果的影响因素。方法回顾性分析该院2008年2月—2010年2月收治的84例老年喉癌患者的临床资料,均实施手术治疗。术后随访5年,了解患者的5年生存情况,并对相关影响因素进行分析。结果经随访有7例患者因联系方式变更失访,随访率为91.67%(77/84)。随访5年,有27例患者死亡,50例患者存活,生存率为59.52%(50/84)。经单因素分析,显著影响患者5年生存情况的因素包括年龄、病理分级、肿瘤大小、原发部位,以及治疗方式和淋巴结转移、TNM分期,均P<0.05。经多因素Cox回归分析,可得原发部位和治疗方式以及淋巴结转移和TNM分期是影响外科手术治疗老年喉癌效果的独立因素,均P<0.05。结论影响外科手术治疗老年喉癌效果的因素包括原发部位和治疗方式以及淋巴结转移和TNM分期。
Objective To investigate the influencing factors of clinical surgical treatment of laryngeal cancer in the elderly. Methods The clinical data of 84 elderly patients with laryngeal cancer admitted to our hospital from February 2008 to February 2010 were analyzed retrospectively. All patients underwent surgical treatment. The patients were followed up for 5 years to understand the patients’ 5-year survival and to analyze the related factors. Results After follow-up, 7 patients were lost due to the change of contact method. The follow-up rate was 91.67% (77/84). During the follow-up of 5 years, 27 patients died and 50 patients survived with a survival rate of 59.52% (50/84). After univariate analysis, factors that significantly influenced the 5-year survival of patients included age, pathological grade, tumor size, primary site, treatment modalities and lymph node metastasis, TNM stage, all P <0.05. The multivariate Cox regression analysis showed that the primary site and treatment, as well as the lymph node metastasis and TNM stage, were the independent factors influencing the surgical treatment of laryngeal cancer in the elderly, both P <0.05. Conclusion The influencing factors of surgical treatment of laryngeal cancer in elderly patients include primary site and treatment, as well as lymph node metastasis and TNM staging.