随着呼吸机在临床上应用越来越普遍,呼吸机引起肺损伤——呼吸机相关性肺损伤(ventilator-induced lung injury,VILI)的发生率也逐渐增高,据文献报道高达15%[1]。VI-LI是机械通气的一种严重并发症,在病理上不仅表现为肺泡外气体,还包括肺泡上皮和血管内皮的广泛破坏、肺水肿和 As ventilator applications become more and more common in the clinic, ventilator-induced lung injury - the incidence of ventilator-induced lung injury (VILI) is also increasing, as reported in the literature up to 15% [1 ]. VI-LI is a serious complication of mechanical ventilation, not only in the pathological manifestations of extra-alveolar gas, but also extensive destruction of the alveolar epithelium and vascular endothelium, pulmonary edema and