目的:调查二、三级综合医院护士职业素养现状及其影响因素，并构建二、三级综合医院护士职业素养常模，为评价护士职业素养水平提供参考。方法:2016年5—12月以护士职业素养评价体系为工具，采用随机整群抽样法，对全国7个地理分区14个城市的35所二、三级综合医院3 315名护士进行调查，并建立均数常模、划界常模、分类常模。结果:二、三级综合医院护士职业素养均数常模总分为（71.02 ± 16.70）分，各维度均数常模得分分别为职业伦理（18.97 ± 4.52）分，综合能力（17.99 ± 4.46）分，专业技能（17.07 ± 4.80）分，职业情感（16.98 ± 4.70）分；根据特征差异形成不同性别、年龄、护龄、学历、职称、职务、科室、婚姻状况、有无子女的分类常模；根据总分划界常模，总分在区间[90.92，100.00）为优，在区间[78.31，90.92）为良，在区间[64.27，78.31）为一般，在区间[50.49，64.27）为较差，在区间[0.00，50.49）为差。结论:二、三级综合医院护士职业素养处于一般水平且受多种因素的影响，医疗管理者和护理管理者应该采取相应的措施以提高护士的职业素养。“,”Objective:To investigate the current situation of nurses′ professionalism in secondary and tertiary general hospitals, analyze its influence factors, and establish norms of nurses′ professionalism in secondary and tertiary hospitals, so as to provide references for evaluation the level of professionalism in nurses.Methods:From May to December 2016, the nurses′ professionalism evaluation system was used to investigate 3 315 nurses in 35 secondary and tertiary general hospitals in 14 cities of 7 regions in China by using random cluster sampling, and the corresponding norm, classification norm and delimitation norm were defined.Results:The average norm scores of nurses′ professionalism in the secondary and tertiary general hospitals was (71.02 ± 16.70), and the average norm scores of each dimension were professional ethics (18.97 ± 4.52) , comprehensive capabilities (17.99 ± 4.46), professional skills (17.07 ± 4.80), professional emotions (16.98 ± 4.70) . According to the differences in characteristics, the classification norms for different gender, age, working years, educational background, professional title, position, department, marital status, with or without children were formed. The level of nurses′ professionalism was divided into five grades: the total score in the interval [90.92, 100.00] was excellent, in the interval [78.31, 90.92) was good, in the interval [64.27, 78.31) was general, in the interval [50.49, 64.27) was relatively poor, in the interval [0.00, 50.49) was poor.Conclusions:Nurses′ professionalism in secondary and tertiary hospitals was in the general level and affected by a variety of factors, medical managers and nursing managers should take corresponding measures to improve nurses′ professionalism.