论文部分内容阅读
卡维地洛(Carvedilol)是一种非选择性的β受体阻滞剂,临床上常作为抗高血压药。本研究表明,该药不影响心脏的频率,可用于治疗心绞痛,特别是治疗左心室功能不全的心绞痛病人,效果良好。 20名患有劳力型心绞痛的患者,首先服用安慰剂2周,然后服卡维地洛25mg一日2次,共2周,再服卡维地尔50mg一日2次,共2周,最后再服安慰剂2周。结果旋踏器运动时间从7.5±0.5分钟(安慰剂)增至9.0±0.5分钟(25mg)和92±0.4分钟(50mg(P<0.001)。1mmST段抑制的平均时
Carvedilol is a nonselective β blocker that is clinically used as an antihypertensive drug. This study shows that the drug does not affect the frequency of the heart, can be used for the treatment of angina pectoris, especially for patients with angina pectoris of left ventricular dysfunction, the effect is good. Twenty patients with labor-type angina first took a placebo for 2 weeks and then served 2 mg of carvedilol 25 mg twice daily for 2 weeks before taking carvedilol 50 mg twice daily for 2 weeks Take a placebo for another 2 weeks. Results Pedunculate time increased from 7.5 ± 0.5 minutes (placebo) to 9.0 ± 0.5 minutes (25 mg) and 92 ± 0.4 minutes (50 mg, P <0.001)