目的对脑立体定向手术治疗帕金森病进行疗效分析。方法按 Ｈｏｅｈｎ和 Ｙａｈｒ病情分级：Ⅰ级 ６６例， Ⅱ级１２９例，Ⅲ级 １５９例，Ⅳ级 １８１例，Ⅴ级４５例。采用丘脑腹外侧核射频热凝毁损治疗。结果早期（１９８０年前）有效率为８２．２％，疗效显著者占６０％，并发症发生率为１５．７％，病死率１．１％。近年来（８０年代末以后）有效率为９８％，疗效显著者占９１％，并发症发生率４．１％，手术病死率０．３％。结论　立体定向手术治疗帕金森病是重要方法之一。 Objective To analyze the curative effect of stereotactic surgery on Parkinson’s disease. Methods According to the Hoehn and Yahr conditions, 66 were grade Ⅰ, 129 were grade Ⅱ, 159 were grade Ⅲ, 181 were Ⅳ and 45 were Ⅴ. Venous thalamic radiofrequency ablation treatment. Results Early (1980) the effective rate was 82.2%, 60% of patients with significant effect, the complication rate was 15.7% and the case fatality rate was 1.1%. In recent years (after the late 1980s), the effective rate was 98%, with a significant effect of 91%, the complication rate was 4.1% and the operative mortality rate was 0.3%. Conclusion Stereotactic surgery for Parkinson’s disease is one of the important methods.