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本文回顾性分析了我院1978～1981年先天性畸形122例。发病率为14.27‰。以神经管畸形最多,占87.35％。致畸因素除遗传因素、环境因素(包括病毒,物理及化学因素等)外,孕妇及其爱人大量吸烟、饮酒有可能是致畸因素之一。为防止和减少畸形儿的出生,应普遍开展婚前检查、禁止近亲结婚,孕期勿滥用药物,预防病毒感染和避免接触放射线。此外,孕早期可测血及羊水中甲胎旦白,羊水细胞培养及其他生化检查,晚期可用超声,x线、羊水镜、羊水造影等方法确诊。
This article retrospectively analyzed our hospital from 1978 to 1981, 122 cases of congenital malformations. The incidence was 14.27 ‰. Most neural tube defects, accounting for 87.35%. Teratogenic factors In addition to genetic factors, environmental factors (including viruses, physical and chemical factors, etc.), pregnant women and their lovers smoking, alcohol consumption may be one of the teratogenic factors. In order to prevent and reduce the birth of deformed children, premarital examination should be carried out generally, marriage of close relatives is prohibited, drugs should be abused during pregnancy, prevention of virus infection and avoidance of exposure to radiation. In addition, early pregnancy can detect blood and amniotic fluid in a fetus white, amniotic fluid cell culture and other biochemical tests, advanced ultrasound, x-ray, amniotic fluid, amniocentesis and other methods of diagnosis.