论文部分内容阅读
目的 探讨冠状动脉内注射腺苷对急性心肌梗死急诊直接PTCA术中无再流现象发生的影响。方法79例急性心肌梗死患者被随机分配到腺苷组 (5 1例 )和非腺苷组 (2 8例 ) ,腺苷给药方法为在每次球囊扩张前及其后冠状动脉内弹丸式注射 2 4～4 8μg。结果 非腺苷组有 8例出现无血流(2 8.6 %) ,腺苷组有 3例出现无血流 (5 .9%)。注射腺苷患者未见明显合并症。结论 对于急性心肌梗死患者 ,急诊PTCA术中冠状动脉内注射腺苷安全有效 ,无再流发生率显著降低 ,因此对改善患者预后具有极为重要的意义。
Objective To investigate the effect of intracoronary injection of adenosine on the occurrence of no-reflow in patients undergoing emergency PTCA with acute myocardial infarction. Methods A total of 79 patients with acute myocardial infarction were randomized to adenosine group (n = 21) and non-adenosine group (n = 28). Adenosine administration was given before and after each balloon dilation Injections 24 ~ 48μg. Results In non-adenosine group, 8 cases showed no blood flow (22.6%) and 3 cases in adenosine group showed no blood flow (5.9%). In patients with adenosine injection no obvious complications. Conclusion In patients with acute myocardial infarction, intracoronary injection of adenosine during emergency PTCA is safe and effective, and the incidence of no-reflow is significantly reduced. Therefore, it is of great importance to improve the prognosis of patients.