自本世纪初以来,临床和实验观察已表明肺部感染可促进矽肺的发生和进展。矽肺病变中有抗原—抗体复合物的存在,以及风湿性关节炎患者的煤尘肺易加重,都提示机体尤其肺部免疫状况是尘肺发生的重要因素。引起气道慢性刺激的物质往往与粉尘一起存 Since the beginning of this century, clinical and experimental observations have shown that pulmonary infection can promote the occurrence and progression of silicosis. The presence of antigen-antibody complexes in silicotic lesions and the increased susceptibility to pneumoconiosis in rheumatoid arthritis patients suggest that the immune status of the body, especially the lungs, is an important factor in pneumoconiosis. Materials that cause chronic airway irritation often coexist with dust