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A 14-year-old girl presented with right upper abdominal swelling for two months. Physical examination revealed palpable hepatomegaly. Her laboratory analysis revealed a mild anemia (HGB: 108 g/L). The tests for liver function were normal. The Child-Pugh score was A grade. The tests for hepatitis B and C viruses were negative. The tests for tumor markers such as carcinoembryonic antigen (CEA),α-fetoprotein (AFP), and cancer antigen 19-9 (CA19-9) were normal. All other laboratory results were within the normal range. Abdominal ultrasound revealed an oval isoechoic mass in the liver measuring 26.4 cm × 25.6 cm × 12.6 cm, which was solid, ill-defined and had rich blood flow signals. Contrast-enhanced CT and MRI of the liver demonstrated a huge hepatic mass of 14.4 cm × 21.5 cm × 22.2 cm, and heterogenous enhancement with central necrosis, which involved all three hepatic veins, the left portal vein and had loss of fat planes with the inferior vena cava (Figure 1A,B). Three-dimensional reconstruction technology revealed that the total hepatic volume was 6,158.3 mL, and the tumor volume was 4,258.68 mL. Furthermore, the standard hepatic volume was 1,105 mL, the remnant liver volume was 1,373 mL (72%), and the indocyanine green clearance test at 15 minutes was 1.2%.