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目的探讨甘精胰岛素联合瑞格列奈治疗2型糖尿病的临床效果。方法选取2014年4月—2015年4月高安市中医院收治的2型糖尿病患者100例,按照治疗方式不同将患者分成参照组与试验组,各50例。参照组患者给予瑞格列奈治疗,试验组在参照组基础上给予甘精胰岛素进行辅助性治疗,比较两组患者治疗总有效率及空腹血糖、餐后2h血糖水平。结果试验组患者总有效率高于参照组,差异有统计学意义(P<0.05)。治疗前两组患者空腹血糖和餐后2h血糖比较,差异无统计学意义(P>0.05);治疗后试验组患者空腹血糖、餐后2h血糖低于参照组,差异有统计学意义(P<0.05)。结论甘精胰岛素联合瑞格列奈治疗2型糖尿病的临床效果确切,可有效控制患者空腹血糖及餐后2h血糖水平。
Objective To investigate the clinical effect of glargine combined with repaglinide on type 2 diabetes mellitus. Methods 100 cases of type 2 diabetic patients admitted from April 2014 to April 2015 in Gao’an Hospital of Traditional Chinese Medicine were divided into the reference group and the experimental group according to the different treatment methods, 50 cases in each group. The patients in the reference group were given repaglinide. The patients in the test group were treated with insulin glargine on the basis of the reference group. The total effective rate, fasting blood glucose and postprandial blood glucose level were compared between the two groups. Results The total effective rate of the experimental group was higher than that of the reference group, the difference was statistically significant (P <0.05). There was no significant difference in fasting blood glucose and postprandial blood glucose between the two groups before treatment (P> 0.05). After treatment, fasting blood glucose and postprandial blood glucose at 2h were lower in the experimental group than in the reference group (P < 0.05). Conclusion Glargine and repaglinide are effective in treating type 2 diabetes mellitus, which can effectively control fasting blood glucose and 2h postprandial blood glucose.