接种乙肝疫苗是预防乙型肝炎病毒感染的最有效方法,医务人员又是乙型肝炎病毒感染的高危人群。2010年笔者对我院997例抗-HBs阴性的医务人员全程接种3剂次国产重组乙型肝炎疫苗后的免疫效果进行调查分析。1流行病学资料1.1受种人群我院997例中,男372例,女625,年龄20~30岁162例,31~40岁336例,41~50岁312例,51~60岁 Vaccination of hepatitis B vaccine is the most effective way to prevent hepatitis B virus infection, and medical staff are at high risk of hepatitis B virus infection. In 2010, the author investigated the immune effect of 997 anti-HBs-negative medical workers in our hospital after three doses of domestic recombinant hepatitis B vaccine. 1 epidemiological data 1.1 population 997 cases in our hospital, 372 males and 625 females, aged 20 to 30 years old in 162 cases, 336 cases of 31 to 40 years old, 41 to 50 years old in 312 cases, 51 to 60 years old