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目的分析荆州市2012-2016年疑似预防接种异常反应(AEFI)监测数据及预防接种安全性。方法采用描述性流行病学方法对荆州市2012-2016年AEFI报告数据进行分析。结果 2012-2016年全市共报告2 830例AEFI,年均报告发生率为38.94/10万剂;其中一般反应2 646例(93.50%,36.41/10万剂)、异常反应157例(5.55%,2.16/10万剂)。各县AEFI报告发生率在13.38/10万剂-151.54/10万剂之间(x2=2002.08,P<0.001);2岁以下病例占84.20%;5-8月份发生病例占51.41%。AEFI在48h内报告率为98.30%,各年报告县覆盖率为100%。结论荆州市AEFI监测运转和预防接种安全性良好;需加强薄弱地区AEFI监测。
Objective To analyze the surveillance data and preventive vaccination safety of suspected immunization inoculation (AEFI) in Jingzhou from 2012 to 2016. Methods A descriptive epidemiological method was used to analyze the AEFI report data from 2012 to 2016 in Jingzhou City. Results A total of 2 830 cases of AEFI were reported in the city from 2012 to 2016, with an average annual incidence of 38.94 / 10 million doses. Among them, 2 646 (93.50%, 36.41 / 10 000) were common reactions and 157 (5.55% 2.16 / 10 million doses). The incidence of AEFI in each county ranged from 13.38 / 100 to 151.54 / 10 000 (x2 = 2002.08, P <0.001). The incidence of AEFI in each county was 84.20% under 2 years old and 51.41% in May-August. AEFI reported a rate of 98.30% within 48h, reporting a 100% coverage of the county in each year. Conclusion The AEFI monitoring operation and vaccination in Jingzhou are safe and safe. AEFI monitoring in weak areas needs to be strengthened.