论文部分内容阅读
Objective:To investigate the cytotoxicity of the crude ethanol extract of the rhizome of Zingiber zerumbel(Z.zerumbet)(L)Smith,and Curcuma zedoaria(C.zedoaria)Rosc,against Artemia salina Leach.Methods:Fresh rhizomes of Z.zerumbet(L)Smith,and C.zedoaria Rose,were extracted separately in cold with ethanol(2.5 L)and after concentration a brownish syrupy suspension of ethanol extracts of Z.zerumbel(L)Smith,and C.zedoaria Rose,was obtained.The cytotoxic effect of the crude ethanol extracts of both plants was determined by brine shrimp lethality bioassay.Results:Crude ethanol extracts of the rhizome of Z.zerumbel(L)Smith,showed the highest cytotoxicity(LC_(50)was 1.24μg/mL)against brine shrimp nauplii as compared with C.zedoaria Rose.(LC_(50)was 33.593μg/mL)after 24 h of exposure.Conclusions:It can be concluded that the rhizome of Z.zerumbet(|L)Smith,and C.zedoaria Rose,can be used as a source of cytotoxic agent.
Objective: To investigate the cytotoxicity of the crude ethanol extract of the rhizome of Zingiber zerumbel (Z.zerumbet) (L) Smith, and Curcuma zedoaria (C.zedoaria) Rosc, against Artemia salina Leach. Methods: Fresh rhizomes of Z.zerumbet (L) Smith, and C.zedoaria Rose, were extracted separately in cold with ethanol (2.5 L) and after concentration a brownish syrupy suspension of ethanol extracts of Z.zerumbel (L) Smith, and C.zedoaria Rose, was obtained. The cytotoxic effect of the crude ethanol extracts of both plants was determined by brine shrimp lethality bioassay. Results: Crude ethanol extracts of the rhizome of Z.zerumbel (L) Smith, showed the highest cytotoxicity (LC_ (50) was 1.24 μg / mL ) against brine shrimp nauplii as compared with C.zedoaria Rose. (LC_ (50) was 33.593 μg / mL) after 24 h of exposure. Conlusions: It can be concluded that the rhizome of Z.zerumbet (| L) Smith, and C.zedoaria Rose, can be used as a source of cytotoxic agent.