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目的观察急性一氧化碳(CO)中毒者心肌受损情况及相关因素。方法对2000年10月至2005年2月住院治疗的急性CO中毒者35例进行临床观察、血清心肌损伤标记物测定和体表心电图(ECG)检查。结果轻、中、重度患者血清心肌损伤标记物的异常率分别为16.67%、42.86%、93.33%,ECG异常率分别为33.33%、57.14%、86.67%。急性CO中毒组间差异均具有显著性意义(P<0.01)。结论急性CO中毒引起的心肌受损十分普遍,且随急性CO中毒程度的加深而显著地增加,在治疗急性CO中毒时应注意保护和营养心肌细胞。
Objective To observe the myocardial damage and related factors of acute carbon monoxide (CO) poisoning. Methods Thirty-five patients with acute CO poisoning who were hospitalized from October 2000 to February 2005 were enrolled in the study. Serum myocardial injury markers and surface electrocardiogram (ECG) were measured. Results The abnormal rates of serum myocardial injury markers in patients with mild, moderate and severe were 16.67%, 42.86% and 93.33% respectively, and the abnormal rates of ECG were 33.33%, 57.14% and 86.67% respectively. The differences between acute CO poisoning groups were significant (P <0.01). Conclusions Myocardial injury caused by acute CO poisoning is very common, and it increases remarkably with the deepening of acute CO poisoning. In the treatment of acute CO poisoning, we should pay attention to the protection and nutrition of myocardial cells.