类风湿性关节炎(rheumatoid arthritis,RA)是一种病因不明的慢性、消耗性、反复发作、以关节症状为主的自身免疫性疾病。多发于女性,其发病率国内尚无精确的统计,估计在1.08%左右,欧美国家的发病率约为0.5%～3.0%。典型的临床表现为反复发作的对称多发性小关节炎,以手、腕、足、膝等关节最常受累。早期可有红、肿、热、痛和关节功 Rheumatoid arthritis (RA) is a chronic, consumptive, recurrent and arthritic autoimmune disease of unknown etiology. Occurred in women, the incidence of the country there is no accurate statistics, estimated at about 1.08%, the incidence in Europe and the United States is about 0.5% to 3.0%. The typical clinical manifestations of recurrent symmetrical polyarthritis, with hands, wrists, feet, knees and other joints most commonly involved. Early may have red, swollen, hot, pain and joint work