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目的了解南宁市手足口病重症及死亡病例流行病学和临床特征。方法调查和收集南宁市2010年1～4月期间42例手足口病重症病例的病历材料,对其流行病学和临床特征进行描述性研究。结果 <3岁儿童占78.5%,男性多于女性,农村地区发病人数占78.57%;重症手足口病治愈组患者和死亡患者临床症状差异无统计学意义(P>0.05);治愈组和死亡组患者到镇医院级别以上就诊时间差异无统计学意义(P>0.05);治愈组和死亡组实验室检测EV71阳性率比较,差异无统计学意义(P>0.05)。结论手足口病重症病例要做到早期诊断、早期治疗存在相当大的困难,因此应采取综合性防制措施。
Objective To understand the epidemiological and clinical features of severe cases and deaths of hand-foot-mouth disease in Nanning city. Methods To investigate and collect the medical records of 42 cases of HFMD in Nanning from January to April in 2010, and to carry out a descriptive study on its epidemiological and clinical features. Results There were 78.5% of children <3 years old, more males than females and 78.57% of the patients in rural areas. There were no significant differences in the clinical symptoms between the patients with severe hand-foot-mouth disease and the patients with death (P> 0.05) There was no significant difference in the time of visiting above the level of town hospital (P> 0.05). There was no significant difference in the positive rate of EV71 between the cured group and the dead group (P> 0.05). Conclusion HFMD cases should be diagnosed early and there are considerable difficulties in early treatment. Therefore, comprehensive prevention and treatment measures should be taken.