寄生于淋巴系统的丝虫,作为一个长期生存的种族,必须在其哺乳动物宿主体内维持一定水平的微丝蚴血症,以保证有足够数量的微丝蚴供蚊媒传播。据此人们产生了这样的论点,即微丝蚴有高度的免疫原性并诱导多种抗体和细胞介导的免疫反应。在大多数适宜的宿主-寄生虫组合中,处于循环中的微丝蚴可维持相当稳定的数量达数月或数年之久。一般认为,这是丝虫繁殖以增加微丝蚴数量和宿主反应以控制微丝蚴血症之间相 The filarial parasites on the lymphatic system, as a long-lived race, must maintain a certain level of microfilaremia in their mammalian hosts to ensure that a sufficient number of microfilariae are available for mosquito transmission. Based on this, people have come to the point that microfilariae are highly immunogenic and induce a variety of antibodies and cell-mediated immune responses. In most suitable host-parasite combinations, the circulating microfilariae can maintain a fairly constant amount for months or years. It is generally accepted that this is a phase of filarial reproduction that increases the number of microfilariae and the host response to control microfilaremia