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射血分数降低的心力衰竭(心衰)具有很高的致死率与致残率,其治疗目前仍然是一大挑战。交感-迷走神经的失衡在射血分数降低的心衰发展过程中起到重要作用,压力反射激活疗法可以降低交感神经的活性并且增加迷走神经的活性,从而打破心衰发展的恶性循环。本文就压力反射激活疗法治疗射血分数降低心衰的研究进展作一综述。
Heart failure with reduced ejection fraction (heart failure) has a high rate of lethality and morbidity and treatment is still a major challenge. Sympathetic-vagal imbalance plays an important role in the development of heart failure with reduced ejection fraction. Stress reflex activation therapy can reduce sympathetic activity and increase vagal activity, thus breaking the vicious cycle of heart failure. This review summarizes the research progress of baroreflex activated therapy in the treatment of heart failure with ejection fraction.