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昼夜节律是指的24小时变化的生物节律。已经发现动物对许多化学物质的生物学反应和敏感性都具有昼夜节律性波动,其发生机理还不十分清楚。为了了解控制室温在23℃时正常光周期(06:00时到18:00时光照)和倒置光周期(18:时到06;00时光照)对动物生物节律的影响,对CF—小鼠肝脏谷胱甘肽(GSH)含量、肝重、肝中r—谷氨酰半胱氨酸合成酶(r—GS)和r—谷氨酰转移酶(r—GT)的活性进行了测定研究。
Circadian rhythm refers to the 24-hour change in the biological rhythm. It has been found that animals have circadian rhythmic fluctuations in the biological response and sensitivity to many chemicals, and its mechanism of action is not well understood. In order to understand the effect on animal biorhythm by controlling the normal circadian rhythm of light at 23 ° C (light time between 06:00 and 18:00) and inverted light period (light time between 18:00 and 06:00), CF- mice The contents of hepatic glutathione (GSH), liver weight, r-glutamylcysteine synthetase (r-GS) and r-glutamyltransferase (r-GT) in liver were measured .