呋苄青霉素,是一个国产新的半合成广谱青霉素。1971年Bodey等报告本品(代号BL-P 1597)与其同类物BL-P 1654具有广谱抗菌活性,体外对绿脓杆菌抗菌作用超过羧苄青霉素,同年Price等报导BL-P1654体内外抗绿脓杆菌作用都比羧苄青霉素强,对阴性杆菌感染小鼠保护作用超过氨苄青霉素。以后,对BL-P 1654的抗菌作用、药物动力学、毒副作用陆续有所报导,但71年以来,一直未再见有关BL-P1597的报告。 Fulin benzylpenicillin, is a new semi-synthetic broad-spectrum penicillin. In 1971, Bodey et al. Reported that the product (code BL-P 1597) and its homologue BL-P 1654 had broad-spectrum antibacterial activity. In vitro antibacterial activity against Pseudomonas aeruginosa exceeded that of carbenicillin. In the same year, Price et al. Pseudomonas aeruginosa role than carbenicillin, negative bacilli in mice protective effect than ampicillin. After the antibacterial effect, pharmacokinetics, side effects on the BL-P 1654 have been reported, but 71 years, has been no good to see the report on BL-P1597.