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侵袭和转移是恶性肿瘤治疗的一大难点。WAVE3可以促进细胞伪足的形成,介导肌动蛋白细胞骨架细胞的重组以增加肿瘤的迁移和侵袭。现就WAVE3在肿瘤侵袭和转移中的作用机制及与肿瘤的相关性的研究进展进行综述。
Invasion and metastasis is a major difficulty in the treatment of malignant tumors. WAVE3 can promote the formation of cell pseudopods, mediating the reorganization of actin cytoskeleton cells to increase the migration and invasion of tumors. The research progress on the mechanism of WAVE3 in tumor invasion and metastasis and its correlation with tumor are reviewed.