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目的:分析300例瘙痒性皮肤病患者皮肤点刺试验变应原检测结果。方法:回顾性分析2019年1月至12月于郑州大学附属儿童医院行皮肤点刺试验(SPT)的300例瘙痒性皮肤病患者的临床资料。结果:300例瘙痒性皮肤病患者中荨麻疹患者118例(39.33%)，特异性皮炎患者147例(49.00%)，湿疹35例(11.67%)，以女性患者居多。吸入组中排名前5的变应原分别为粉尘螨(67.00%)、屋尘螨(61.33%)、蟑螂(48.67%)、狗皮屑(25.67%)与禾本谷类(23.67%)，食入组排名前5的变应原分别为牛奶(45.67%)、鸡蛋(42.33%)、小虾(28.33%)、蟹肉(21.67%)与黑胡椒(19.33%)。不同性别及不同疾病患者粉尘螨、屋尘螨等主要变应原阳性率比较差异未见统计学意义(n P>0.05)，但不同年龄组患者这些主要变应原阳性率比较差异有统计学意义(n P0.05), but there were statistically significant differences in the positive rates of the main allergens among patients of different age groups (n P<0.05).n Conclusions:The skin prick test allergen detection can effectively find allergens. Among them, dermatophagoides farinae, dermatophagoides pteronyssinus, cockroaches, dog dander, grass cereals, milk, eggs, shrimps, crab meat and black pepper are the main allergens, and can provide a scientific basis for the prevention and treatment of common itching skin diseases.