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本实验室曾报道,六味地黄煎剂对小鼠实验性肝损伤有保护作用,能显著降低CCl_4中毒小鼠及硫代乙酰胺引起的小鼠谷丙转氨酶活性升高。为进一步探讨六味地黄配方组成的合理性及其与保肝作用关系,本实验考察了其拆方后“三补”、“三泻”对小鼠SGPT活性升高的影响。
The laboratory has reported that Liu Wei Di Huang Decoction has a protective effect on experimental liver injury in mice, can significantly reduce the CCl_4 poisoning mice and thioacetamide-induced elevated alanine aminotransferase activity in mice. To further explore the rationality of the composition of Liu Wei Di Huang and its relationship with hepatoprotective effects, this experiment examined the effect of “San Bu” and “San Xie” on the increase of SGPT activity in mice after decomposed prescription.