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我们最近见到毛细胞性白血病(Hairy Cell Leukemia HCL),1例并经电镜检查证实。兹将临床所见及检查情况报导如下。病例报告例:患儿宋××,女,4岁10个月。1976年8月起病,因不规则发热伴周身关节疼痛,经抗风湿治疗约半年无效,于1977年2月在农村经某部队医院检查骨髓,诊断为“恶网”后,用环磷酰胺及强的松治疗,症状缓解,但近日纳差。于1977年4月来我院门诊检查,当时一般情况尚可,满月脸,皮肤无出血点,浅表淋巴结不肿大,心,肺阴性,腹软,肝肋沿下锁骨中线上2厘米,脾肋下3厘米。经门诊骨髓穿刺涂片以瑞氏染色在普通光学显微镜下观察形态,见到原始血细胞96.5%,中性分叶粒、杆状核粒及嗜酸晚幼粒细胞各占0.5%,淋巴细胞2%;同时在周围血象中亦见到原始血细胞78%,
We recently saw Hairy Cell Leukemia (HCL), one case confirmed by electron microscopy. The clinical findings and inspection reports below. Case report: Children Song × ×, female, 4-year-old 10 months. August 1976 onset, due to irregular fever with peri-articular pain, anti-rheumatic treatment of about six months ineffective, in February 1977 in the countryside through a military hospital check bone marrow, diagnosed as “evil net”, with cyclophosphamide And prednisone treatment, symptoms, but the recent anorexia. In April 1977 to our hospital clinic examination, when the general situation is acceptable, full moon face, no bleeding skin, superficial lymph nodes, heart, lung-negative, abdominal soft, liver ribs along the middle of the clavicle 2 cm, Spleen ribs 3 cm. The outpatient bone marrow aspirate smear by Wright’s stain observed under ordinary light microscope morphology, see the original 96.5% of blood cells, neutral leaf granules, rod nuclei and eosinophils late each of 0.5%, lymphocytes 2 %; At the same time in the peripheral blood also saw 78% of the original blood cells,