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患者男性,56岁,因咳嗽、低热,伴乏力1月余,以肺结核Ⅲ上/上菌(集一)进展期收住。入院前已给予INH、RFP、SM三联抗痨治疗近20d,INH为口服300mg/d,服药后无不适感。入院后改INH为静脉点滴,300mg/d,其他治疗同前。静点数日后病人出现两下肢疼痛,无力感,并伴轻度跛行。查:行走时轻度跛行,但两下肢皮肤无感觉异常,腱反射无增强及减弱,病理反射未引出。考虑可能为INH静点而引起,给予Vit B_6100mg入液静点亦不能消除症状,故停止静脉点滴INH,仍给予口服,两下肢疼痛消失,无力感、跛行渐消失。20d后病
Male patient, 56 years old, due to cough, fever, with fatigue for more than a month to tuberculosis Ⅲ on / bacteria (set) Progressive admission. Before admission has been given INH, RFP, SM triple anti-tuberculosis treatment nearly 20d, INH oral 300mg / d, after taking no discomfort. Change INH after admission to intravenous drip, 300mg / d, other treatment with the previous. After a few days the patient appeared two lower extremity pain, powerlessness, accompanied by mild limp. Check: walking mild lameness, but no abnormalities in both lower extremity skin, tendon reflex no enhancement and attenuation, pathological reflex did not lead. Consider may be caused by INH static point, give Vit B_6100mg intravenous injection can not eliminate the symptoms, so stop intravenous INH, still given oral, two lower extremity pain disappeared, powerlessness, limp disappeared. After 20d disease